Limonoids from the Twigs and Leaves of Chukrasia tabularis

被引:23
|
作者
Zhang, Chuan-Rui [1 ]
Yang, Sheng-Ping [1 ]
Chen, Xne-Qin [1 ]
Wu, Yan [1 ]
Zhen, Xue-Chu [1 ]
Yue, Jian-Min [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
关键词
D O I
10.1002/hlca.200890254
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Seven new limonoids, tabularisins J-P (1-7, resp.), together with eight known compounds, were isolated from the twigs and leaves of Chukrasia tabularis. Their structures were determined primarily by spectroscopic methods. The potassium channel blocking activities of some of these isolates were evaluated, and a few of them exerted significant activities on the delayed rectifier (I-K) K+ current.
引用
收藏
页码:2338 / 2350
页数:13
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