Penetration of rifampin through Staphylococcus epidermidis biofilms

被引：140
|
作者：
Zheng, ZL
Stewart, PS [1 ]
机构：
[1] Montana State Univ, Ctr Biofilm Engn, Bozeman, MT 59717 USA
[2] Montana State Univ, Dept Chem Engn, Bozeman, MT 59717 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 03期
关键词：
D O I：
10.1128/AAC.46.3.900-903.2002
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Rifampin penetrated biofilms formed by Staphylococcus epidermidis but failed to effectively kill the bacteria. Penetration was demonstrated by a simple diffusion cell bioassay and by transmission electron microscopic observation of antibiotic-affected cells at the distal edge of the biofilm.
引用
收藏
页码：900 / 903
页数：4
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