Diagnosis of influenza from lower respiratory tract sampling after negative upper respiratory tract sampling

被引：16
|
作者：
Bogoch, Isaac I. [1 ,2 ,3 ,4 ]
Andrews, Jason R. [3 ,4 ]
Zachary, Kimon C. [3 ,4 ]
Hohmann, Elizabeth L. [3 ,4 ]
机构：
[1] Toronto Gen Hosp, Div Internal Med, Toronto, ON, Canada
[2] Toronto Gen Hosp, Div Infect Dis, Toronto, ON, Canada
[3] Massachusetts Gen Hosp, Div Infect Dis, Boston, MA 02114 USA
[4] Harvard Univ, Sch Med, Boston, MA USA
来源：
VIRULENCE | 2013年 / 4卷 / 01期
关键词：
influenza; human; H1N1; virus; bronchoalveolar lavage; polymerase chain reaction; INFECTION; ADULTS; VIRUS;
D O I：
10.4161/viru.22466
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In this retrospective cohort study, we demonstrate that PCR-confirmed diagnoses of influenza were made solely by lower respiratory sampling in 6.9% of cases, as traditional upper respiratory tract tests were negative, indeterminate or not performed. Clinical features of these cases are presented. Clinicians should consider lower respiratory tract sampling in select cases of influenza-like illness for diagnosis.
引用
收藏
页码：82 / 84
页数：3
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