An exact confidence interval for the ratio of two related proportions

被引：0
|
作者：
Parker, RA
机构：
[1] BETH ISRAEL HLTH CARE,BIOMETR CTR GZ814,BOSTON,MA 02215
[2] HARVARD UNIV,SCH MED,BOSTON,MA
来源：
BIOMETRICAL JOURNAL | 1996年 / 38卷 / 03期
关键词：
cystic fibrosis; genetic screening; population prevalence; relative risk; sensitivity; specificity;
D O I：
10.1002/bimj.4710380313
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
I propose an exact confidence interval for the ratio of two proportions when the proportions are not independent. One application is to estimate the population prevalence using a screening test with perfect specificity but imperfect sensitivity. The population prevalence is the ratio of the observed prevalence divided by the test's sensitivity. I describe a method to calculate exact confidence intervals for this problem and compare these results with approximate confidence intervals given previously.
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页码：375 / 384
页数：10
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