Layered Double Hydroxides (LDHs) are a group of hydrotalcite-like nano-sizedmaterials with cationic layers and exchangeable interlayer anions. The wide range of divalent and trivalent cationicmetals and anionic compounds are employed in the synthesis of LDH materials, which have improved their importance among the researchers. Because of their high anion exchange property, memory effect, tunable behavior, bio-friendly, simple preparation, and their affordability, these nano-materials are essentially interested today. Modification of LDHs improves their behaviours tomake them appropriate in industrial fields, including biological, adsorbent, mechanical, optical, thermal, electrical fields, etc. This reviewhas critically discussed the structural features, main properties, and also clarified the most important methods of modification and intercalation of LDH nano-materials. Moreover, some novel reported researches related to the successful modification of LDH materials have been characterized and briefly the advantages, disadvantages, and applications are presented in the industrial fields. (C) 2020 Elsevier B.V. All rights reserved.