t(1;19)(q23;p13) in a case of acute monocytic leukemia

被引：3
|
作者：
Weh, HJ
Jonveaux, P
Seeger, D
Felgner, J
Hossfeld, DK
机构：
[1] INST GENET MOLEC,INSERM U301,PARIS,FRANCE
[2] CHRISTIAN ALBRECHTS UNIV KIEL,INST HEMATOPATHOL,KIEL,GERMANY
来源：
CANCER GENETICS AND CYTOGENETICS | 1996年 / 87卷 / 01期
关键词：
D O I：
10.1016/0165-4608(95)00238-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Translocation (1;19)(q23;p13) is considered a specific chromosome aberration in acute lymphoblastic leukemia (ALL). We report a case of M5 acute nonlymphocytic leukemia (ANLL) with t(1;19). In all mitoses studied from peripheral blood (PB) cells, the pathological karyotype 51,XX, t(1;19)(q23;p13), + 8, + der(19)t(1;19)(q23;p13), + 3mar was detected. No rearrangement of the E2A gene was detected. We believe this case shows that cytogenetically indistinguishable aberrations may be accompanied by quite different molecular events.
引用
收藏
页码：52 / 54
页数：3
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