Provision of CD4+T cell help preferentially enhances anti-tumor immunity of high avidity T cells

被引:0
|
作者
Zhu, Zigiang [1 ]
Singh, Vinod [1 ]
Bronte, Vincenzo [2 ]
Feigenbaum, Lionel [3 ]
Hurwitz, Arthur [1 ]
机构
[1] NCI, CCR, CIP, LMI,NIH, Frederick, MD 21701 USA
[2] Univ Padua, Padua, Italy
[3] SAIC Frederick, Frederick, MD USA
来源
JOURNAL OF IMMUNOLOGY | 2010年 / 184卷
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
131.19
引用
收藏
页数:1
相关论文
共 50 条
  • [1] CD4+T cell help differentially influences anti-tumor immunity as a function of T cell avidity
    Zhu, Ziqiang
    Singh, Vinod
    Bronte, Vincenzo
    Feigenbaum, Lionel
    Hurwitz, Arthur
    [J]. CANCER RESEARCH, 2011, 71
  • [2] Provision of CD4+T Cell Help Prevents Tolerization of Tumorspecific CTLs and Enhances Tumor Immunity in a Murine Model of Prostate Cancer
    Shafer-Weaver, Kimberly A.
    Watkins, Stephanie K.
    Malyguine, Anatoli
    Hurwitz, Arthur A.
    [J]. JOURNAL OF IMMUNOTHERAPY, 2008, 31 (09) : 925 - 925
  • [3] CD4+ T Cell Help Selectively Enhances High-Avidity Tumor Antigen-Specific CD8+ T Cells
    Zhu, Ziqiang
    Cuss, Steven M.
    Singh, Vinod
    Gurusamy, Devikala
    Shoe, Jennifer L.
    Leighty, Robert
    Bronte, Vincenzo
    Hurwitz, Arthur A.
    [J]. JOURNAL OF IMMUNOLOGY, 2015, 195 (07): : 3482 - 3489
  • [4] Increased frequency and activation of CD4+ T cells enhances anti-tumor immunity.
    Brown, DM
    Woodward, JG
    Frelinger, JG
    Lord, EM
    [J]. FASEB JOURNAL, 2000, 14 (06): : A1015 - A1015
  • [5] Low avidity CD8+ T cells are less exhausted than their high avidity counterparts and provide superior anti-tumor immunity
    Singhaviranon, Summit
    Dempsey, Joseph
    Hagymasi, Adam
    Mandoiu, Ion
    Srivastava, Pramod K.
    [J]. JOURNAL OF IMMUNOLOGY, 2023, 210 (01):
  • [6] ROLE OF P21 IN CD4+T CELLS IN THE ANTI-TUMOR RESPONSE
    Thoma, Oana-Maria
    Matthe, Diana
    Schurer, Hendrik
    Kramer, Viktoria
    Menchicchi, Bianca
    Neurath, Markus
    Waldner, Maximilian
    [J]. GASTROENTEROLOGY, 2020, 158 (06) : S295 - S295
  • [7] Bystander Activation and Anti-Tumor Effects of CD8+T Cells Following Interleukin-2 Based Immunotherapy Is Independent of CD4+T Cell Help
    Monjazeb, Arta M.
    Tietze, Julia K.
    Grossenbacher, Steven K.
    Hsiao, Hui-Hua
    Zamora, Anthony E.
    Mirsoian, Annie
    Koehn, Brent
    Blazar, Bruce R.
    Weiss, Jonathan M.
    Wiltrout, Robert H.
    Sckisel, Gail D.
    Murphy, William J.
    [J]. PLOS ONE, 2014, 9 (08):
  • [8] CD4+T cell-mediated anti-tumor immunity generated by vaccination with ECP-generated DC
    Hanlon, D. J.
    Han, P.
    Robinson, E.
    Filler, R.
    Khalil, D.
    Edelson, R.
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2016, 136 (05) : S40 - S40
  • [9] Enhancing the strength and durability of vaccine-induced anti-tumor immunity with CD27 agonism of CD4+T cells
    Hwang, Bin-Jin
    Crosby, Erika
    Trotter, Timothy
    Tsao, Li-Chung
    Wang, Tao
    Liu, Congxiao
    Yang, Xiao
    Lei, Gangjun
    Wei, Junping
    Ma, Xingru
    Liu, Bushanqing
    Hobeika, Amy
    Morse, Michael
    Keler, Tibor
    He, Li-Zhen
    Lyerly, Herbert Kim
    Hartman, Zachary
    [J]. CANCER RESEARCH, 2024, 84 (06)
  • [10] Activin-A impedes the establishment of CD4+ T cell exhaustion and enhances anti-tumor immunity in the lung
    Morianos, Ioannis
    Tsitsopoulou, Aikaterini
    Potaris, Konstantinos
    Valakos, Dimitrios
    Fari, Ourania
    Vatsellas, Giannis
    Bostantzoglou, Clementine
    Photiades, Andreas
    Gaga, Mina
    Xanthou, Georgina
    Semitekolou, Maria
    [J]. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2021, 40 (01)