Neuregulin-1 alpha, the underestimated molecule: emerging new roles in normal brain function and the pathophysiology of schizophrenia?

被引:4
|
作者
Bernstein, Hans-Gert [1 ]
Bogerts, Bernhard [1 ]
机构
[1] Univ Magdeburg, Dept Psychiat, D-39120 Magdeburg, Germany
关键词
neuregulin-1; alpha; brain function; schizophrenia; gene regulation; immunocytochemistry; PREFRONTAL CORTEX; EXPRESSION;
D O I
10.1139/gen-2013-0171
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
We comment here, from a schizophrenia research perspective, on a recent paper of Ghahramani Seno et al., which clearly shows that the splice variant neuregulin-1 alpha is able to regulate multiple genes involved in phosphorylation, acetylation, and generation of splice variants.
引用
收藏
页码:703 / 704
页数:2
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