A novel and efficient synthesis of chiral C2-symmetric 1,4-diamines

被引：10

作者：

Xu, Lianhong ^{[1
]}

Desai, Manoj C. ^{[1
]}

Liu, Hongtao ^{[1
]}

机构：

[1] Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 05期

关键词：

C-2-symmetric 1,4-diamines; Corey-Winter olefination; HIV PROTEASE; ENANTIOSELECTIVE SYNTHESIS; DIMERIZATION;

D O I：

10.1016/j.tetlet.2008.11.071

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient method for synthesis of (R,R)- and (S,S)-C-2-symmetric 1,4-diamines was established. The key steps ate a combination of Pinacol Coupling and Corey-Winter olefination. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：552 / 554

页数：3

共 50 条

[1] Dibenzofuran-based C2-Symmetric Chiral Diamines: Their Synthesis and Chiral Recognition Properties
Ito, Suguru
Ikeda, Kengo
Asami, Masatoshi
[J]. CHEMISTRY LETTERS, 2016, 45 (12) : 1379 - 1381
[2] Efficient synthesis of chiral C2-symmetric diamines via allylboration of bis-N,N′-metallodiimines
Ramachandran, P. Veeraraghavan
Biswas, Debanjan
Krzeminski, Marek P.
Chen, Guang-Ming
[J]. TETRAHEDRON LETTERS, 2010, 51 (02) : 332 - 336
[3] An efficient synthesis of C2-symmetric chiral binaphthyl ketone catalysts
Furutani, T
Hatsuda, M
Shimizu, T
Seki, M
[J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2001, 65 (01) : 180 - 184
[4] Selective synthesis of [2+2] macrocyclic Schiff bases from chiral 1,4-diamines
Zhu Hai-Bin
Hu Da-Hua
Dong Hua-Ze
Li Gen-Xi
Guo Shao-Hua
[J]. CHINESE JOURNAL OF CHEMISTRY, 2007, 25 (03) : 343 - 345
[5] Organocatalytic Knoevenagel condensation by chiral C2-symmetric tertiary diamines
Gu, Xiaoyu
Tang, Yan
Zhang, Xiang
Luo, Zinbin
Lu, Hongfei
[J]. NEW JOURNAL OF CHEMISTRY, 2016, 40 (08) : 6580 - 6583
[6] Synthesis and Cytotoxic Evaluation of Novel Platinum(II) Complexes with C2-Asymmetric and C2-Symmetric Chiral Vicinal Diamines
Zhang, Chen
Liu, Hongrui
Yang, Qing
Chang, Jun
Sun, Xun
[J]. CHINESE JOURNAL OF CHEMISTRY, 2013, 31 (01) : 154 - 158
[7] CoII and RhI complexes with C2-symmetric chiral diamines of the dioxolane series
Nindakova, LO
Chipanina, NN
Turchaninov, VK
Ustinov, MV
Shainyan, BA
[J]. RUSSIAN CHEMICAL BULLETIN, 2005, 54 (10) : 2343 - 2347
[8] CoII and RhI complexes with C2-symmetric chiral diamines of the dioxolane series
L. O. Nindakova
N. N. Chipanina
V. K. Turchaninov
M. V. Ustinov
B. A. Shainyan
[J]. Russian Chemical Bulletin, 2005, 54 : 2343 - 2347
[9] Synthesis of chiral C2-symmetric binucleating ligands
Fahrni, CJ
Pfaltz, A
[J]. HELVETICA CHIMICA ACTA, 1998, 81 (03) : 491 - 506
[10] C2-Symmetric diamines and their derivatives as promising organocatalysts for asymmetric synthesis
Zlotin, S. G.
Kochetkov, S. V.
[J]. RUSSIAN CHEMICAL REVIEWS, 2015, 84 (11) : 1077 - 1099

← 1 2 3 4 5 →