Successful long-term application of highly purified natural interferon-alpha (Multiferon®) after preceding interferon approaches in a chronic hepatitis C patient with thrombocytopenia

被引:3
|
作者
Musch, E
Malek, M
von Eick, H
Chrissafidou, A
机构
[1] Marienhosp Bottrop gGmbH, Dept Gen Internal Med, DE-46236 Bottrop, Germany
[2] Univ Bonn, Hosp Med, Dept Internal Med, D-5300 Bonn, Germany
关键词
D O I
10.1080/00365540410019561
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Treatment approaches with recombinant IFN-alpha2b and natural IFN-beta in a patient with chronic hepatitis C (genotype 1b) and cirrhosis had, in both cases, to be terminated prematurely due to breakthrough phenomena and thrombo-leukocytopenia up to WHO grade 3. After the patient was switched to highly purified natural IFN-alpha (Multiferon(R)) the thrombocyte and leukocyte counts increased significantly, and sustained complete biochemical and virological response could be achieved.
引用
收藏
页码:395 / 399
页数:6
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