Hyperglycosylated ferritin in sera of HIV-1-infected patients treated with highly active antiretroviral therapy

被引：3
|
作者：
Malvoisin, E
Livrozet, JM
Ducluzeau, PH
Makloufi, D
Cohen, R
Vincent, N
机构：
[1] Fédération de Biochimie, Hôpital Edouard Herriot, CHU-Lyon
[2] Département de Transplantation et Immunologie Clinique, Hôpital Edouard Herriot, CHU-Lyon
[3] Service de Diabétologie, CHU-Angers
[4] Groupe Immunité des Muqueuses et Agents Pathogènes, CHU-Saint-Etienne
来源：
AIDS | 2006年 / 20卷 / 03期
关键词：
D O I：
10.1097/01.aids.0000199824.26618.62
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A study was conducted to determine the relationship between ferritin and glycosylated isoforms of ferritin and insulin resistance in 69 HIV-infected men receiving HAART. Ferritin levels were significantly correlated with aspartate aminotransferase, alanine aminotransferase, bilirubin and with insulin resistance. The ferritin isoelectric focusing patterns of five insulin-resistant HIV-infected patients under HAART showed large amounts of hyperglycosylated isoforms, which was not found in 56 control subjects and 46 untreated HIV-1-infected patients.
引用
收藏
页码：457 / 459
页数：3
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