Network model of synaptic modification induced by time-structured stimuli in the hippocampal CA1 area

被引:2
|
作者
Tatsuno, M [1 ]
Aizawa, Y [1 ]
机构
[1] Waseda Univ, Dept Appl Phys, Shinjuku Ku, Tokyo 1698555, Japan
关键词
hippocampus; memory; LTP; chaos; spikes;
D O I
10.1016/S0925-2312(99)00033-8
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
A simple neuron network model of the CA1 area of the hippocampus was constructed to investigate the relationship between the time structure of impulses and synaptic modification. By extensive numerical simulation, it was found that most of the experimental data were reproduced, and that chaotic stimuli on the border of the stationary and non-stationary regimes had the largest effect on the amplitude of LTP. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:541 / 549
页数:9
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