Scalability of forces in mesh-based models of elastic objects

Recently, there has been a lot of progress in many areas of biomedical engineering achieved as a result of modeling the objects of interest and then performing in-sHico experiments with them. One of these areas is modeling blood and its components for various applications. We present a short description of such application and a mesh-based approach to modeling. We discuss which elastic forces in this model are scalable, which are not and demonstrate that mesh differences and characteristics of simulation experiments have to be taken into account when calibrating elastic coefficients. The corresponding simulations are performed using our object-in-fluid framework as a part of extensible simulation package ESPResSo.