Chemical constituents, anticancer, antimicrobial and antioxidant activities of essential oil from Anaphalis lacteal grown in Qinghai-Tibet Plateau

被引：2
|
作者：
Liu, Shi-Jun [1 ,2 ]
Liao, Zhi-Xin [1 ,2 ]
Liu, Chao [1 ,3 ]
Sun, Jin-Yue [3 ]
机构：
[1] Southeast Univ, Sch Chem & Chem Engn, Dept Pharmaceut Engn, Nanjing 211189, Jiangsu, Peoples R China
[2] Southeast Univ, Jiangsu Prov Hitech Key Lab Biomed Res, Nanjing 211189, Jiangsu, Peoples R China
[3] Shandong Acad Agr Sci, Inst Agrofood Sci & Technol, Jinan 250100, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2015年 / 29卷 / 14期
关键词：
Anaphalis lacteal; compositae; chemical constituents; anticancer; antimicrobial; antioxidant activities;
D O I：
10.1080/14786419.2014.997728
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The chemical constituent of the essential oil from Anaphalis lacteal was determined; 31 compounds, representing 93.91% of the total oil, were identified by gas chromatography-mass spectrometry analysis. Three Gram-positive bacteria species, three Gram-negative bacteria species and four fungi were used to determine antimicrobial activity; the results revealed that the essential oil had a remarkable antimicrobial effect against bacteria and a susceptive effect against fungus. The oil also possessed more efficient free-radical scavenging activities than butylated hydroxytoluene (BHT) with 50% inhibitory concentration (IC50) value 31g/mL (40g/mL for BHT). MTT assay illustrated that the oil expressed certain effect in inhibiting the growth of HeLa and Hep-6 cancer cells.
引用
收藏
页码：1369 / 1371
页数：3
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