Boosting Deep Learning Risk Prediction with Generative Adversarial Networks for Electronic Health Records

被引:97
|
作者
Che, Zhengping [1 ]
Cheng, Yu [2 ]
Zha, Shuangfei [3 ]
Sun, Zhaonan [4 ]
Liu, Yan
机构
[1] Univ Southern Calif, Los Angeles, CA 90089 USA
[2] IBM Thomas J Watson Res Ctr, AI Fdn, Yorktown Hts, NY 10598 USA
[3] SUNY Binghamton, Binghamton, NY 13902 USA
[4] IBM Thomas J Watson Res Ctr, Yorktown Hts, NY 10598 USA
基金
美国国家科学基金会;
关键词
electronic health record; generative adversarial network; health care; deep learning; CLASSIFICATION; CANCER;
D O I
10.1109/ICDM.2017.93
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
The rapid growth of Electronic Health Records (EHRs), as well as the accompanied opportunities in Data-Driven Healthcare (DDH), has been attracting widespread interests and attentions. Recent progress in the design and applications of deep learning methods has shown promising results and is forcing massive changes in healthcare academia and industry, but most of these methods rely on massive labeled data. In this work, we propose a general deep learning framework which is able to boost risk prediction performance with limited EHR data. Our model takes a modified generative adversarial network namely ehrGAN, which can provide plausible labeled EHR data by mimicking real patient records, to augment the training dataset in a semi-supervised learning manner. We use this generative model together with a convolutional neural network (CNN) based prediction model to improve the onset prediction performance. Experiments on two real healthcare datasets demonstrate that our proposed framework produces realistic data samples and achieves significant improvements on classification tasks with the generated data over several stat-of-the-art baselines.
引用
收藏
页码:787 / 792
页数:6
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