Hereditary multiple exostoses and cancer risk

被引：0

作者：

Porter, DE ^{[1
]}

Simpson, AHRW ^{[1
]}

机构：

[1] Univ Oxford, Nuffield Dept Orthopaed Surg, Nuffield Orthopaed Ctr, Oxford OX1 2JD, England

来源：

FAMILIAL CANCER AND PREVENTION: MOLECULAR EPIDEMIOLOGY - A NEW STRATEGY TOWARD CANCER CONTROL | 1999年

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hereditary multiple exostosis is a common inherited musculoskeletal condition with analogy to several familial malignant traits. Causative loss-of-function mutations in the EXT tumor suppressor gene family have recently been identified. Present strategies to identify malignant change within osteochondromas and future roles for molecular biology are discussed.

引用

页码：515 / 521

页数：7

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