A Convenient Human Hepatocyte Model for Molecular Mechanisms in Caffeine Preconditioning and Protection from Acetaminophen (APAP)-Induced Hepatotoxicity

被引:0
|
作者
Gupta, Priya [1 ,2 ,3 ]
Sharma, Yogeshwar [1 ,2 ,3 ]
Bandi, Sriram [1 ,2 ,3 ]
Vishwanathan, Preeti [1 ,2 ,3 ]
Gupta, Sanjeev [1 ,2 ,3 ]
机构
[1] Childrens Hosp Montefiore, Div Pediat Gastroenterol, Dept Med, Bronx, NY USA
[2] Childrens Hosp Montefiore, Div Pediat Gastroenterol, Dept Pathol, Bronx, NY USA
[3] Albert Einstein Coll Med, Bronx, NY 10467 USA
来源
FASEB JOURNAL | 2015年 / 29卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1004.12
引用
收藏
页数:1
相关论文
共 50 条
  • [1] THE MECHANISMS OF COBALT CHLORIDE-INDUCED PROTECTION AGAINST ACETAMINOPHEN HEPATOTOXICITY
    ROBERTS, SA
    PRICE, VF
    JOLLOW, DJ
    DRUG METABOLISM AND DISPOSITION, 1986, 14 (01) : 25 - 33
  • [2] HepaRG Cells: A Human Model to Study Mechanisms of Acetaminophen Hepatotoxicity
    McGill, Mitchell R.
    Yan, Hui-Min
    Ramachandran, Anup
    Murray, Gordon J.
    Rollins, Douglas E.
    Jaeschke, Hartmut
    HEPATOLOGY, 2011, 53 (03) : 974 - 982
  • [3] MECHANISM OF KETONE-INDUCED PROTECTION FROM ACETAMINOPHEN HEPATOTOXICITY IN THE RAT
    PRICE, VF
    JOLLOW, DJ
    DRUG METABOLISM AND DISPOSITION, 1983, 11 (05) : 451 - 457
  • [4] The molecular mechanisms of acetaminophen-induced hepatotoxicity and its potential therapeutic targets
    Luo, Guangwen
    Huang, Lili
    Zhang, Zhaowei
    EXPERIMENTAL BIOLOGY AND MEDICINE, 2023, 248 (05) : 412 - 424
  • [5] Arjunolic acid, a triterpenoid saponin, prevents acetaminophen (APAP)-induced liver and hepatocyte injury via the inhibition of APAP bioactivation and JNK-mediated mitochondrial protection
    Ghosh, Jyotirmoy
    Das, Joydeep
    Manna, Prasenjit
    Sil, Parames C.
    FREE RADICAL BIOLOGY AND MEDICINE, 2010, 48 (04) : 535 - 553
  • [6] A monkey model of acetaminophen-induced hepatotoxicity; phenotypic similarity to human
    Tamai, Satoshi
    Iguchi, Takuma
    Niino, Noriyo
    Mikamoto, Kei
    Sakurai, Ken
    Sayama, Ayako
    Shimoda, Hitomi
    Takasaki, Wataru
    Mori, Kazuhiko
    JOURNAL OF TOXICOLOGICAL SCIENCES, 2017, 42 (01): : 73 - 84
  • [7] Protection of mice from acetaminophen-induced hepatotoxicity by a sulfhydryl-protected prodrug of glutathione.
    Crankshaw, DL
    Berkeley, LI
    Cohen, JF
    Nagasawa, HT
    TOXICOLOGICAL SCIENCES, 2003, 72 : 350 - 350
  • [8] Acetaminophen (APAP)-Induced Hepatotoxicity and Failure of Liver Regeneration Results from Cellular DNA Damage and Replicative Stress that is Reversed via Paracrine Signaling From Healthy Transplanted Cells and Offers New Therapeutic Mechanisms
    Viswanathan, Preeti
    Bandi, Sriram
    Gupta, Sanjeev
    HEPATOLOGY, 2013, 58 : 256A - 257A
  • [9] The immunological mechanisms and therapeutic potential in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity
    Li, Qianhui
    Chen, Feng
    Wang, Fei
    CELL AND BIOSCIENCE, 2022, 12 (01):
  • [10] The immunological mechanisms and therapeutic potential in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity
    Qianhui Li
    Feng Chen
    Fei Wang
    Cell & Bioscience, 12