Protein Crystallization under Microgravity Conditions. Analysis of the Results of Russian Experiments Performed on the International Space Station in 2005-2015

被引:19
|
作者
Boyko, K. M. [1 ,2 ]
Timofeev, V. I. [1 ,3 ]
Samygina, V. R. [1 ,3 ]
Kuranova, I. P. [1 ,3 ]
Popov, V. O. [1 ,2 ]
Koval'chuk, M. V. [1 ,3 ]
机构
[1] Natl Res Ctr, Kurchatov Inst, Pl Akad Kurchatova 1, Moscow 123098, Russia
[2] Russian Acad Sci, Fed Res Ctr Fundamentals Biotechnol, Leninskii Pr 33, Moscow 119071, Russia
[3] Russian Acad Sci, Shubnikov Inst Crystallog, Fed Sci Res Ctr Crystallog & Photon, Leninskii Pr 59, Moscow 119333, Russia
基金
俄罗斯科学基金会;
关键词
PURINE NUCLEOSIDE PHOSPHORYLASE; SHEWANELLA-ONEIDENSIS MR-1; COUNTER-DIFFUSION METHOD; X-RAY DIFFRACTION; ESCHERICHIA-COLI; 3-DIMENSIONAL STRUCTURE; CRYSTAL-STRUCTURE; PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE; THYMIDINE PHOSPHORYLASE; CARBOXYPEPTIDASE-T;
D O I
10.1134/S1063774516050059
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
Conditions of mass transport to growing crystals have a considerable effect on the crystal size and quality. The reduction of convective transport can help improve the quality of crystals for X-ray crystallography. One approach to minimizing convective transport is crystallization in a microgravity environment, in particular, in space. The data obtained by our research team in protein crystallization experiments on the International Space Station are surveyed and analyzed.
引用
收藏
页码:718 / 729
页数:12
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