Rab3A small GTP-binding protein in Ca2+-dependent exocytosis

被引:99
|
作者
Takai, Y
Sasaki, T
Shirataki, H
Nakanishi, H
机构
[1] OSAKA UNIV,SCH MED,DEPT MOL BIOL & BIOCHEM,SUITA,OSAKA 565,JAPAN
[2] RES DEV CORP JAPAN,ERATO,TAKAI BIOTIMER PROJECT,KOBE 65122,JAPAN
关键词
D O I
10.1046/j.1365-2443.1996.00257.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
There exists a small GTP-binding protein (G protein) superfamily, consisting of more than 50 members, from yeast to mammal. The Rab family belongs to this superfamily and is implicated in intracellular vesicle trafficking. Rab3A small G protein is a member of the Rab3 subfamily which belongs to this Rab family. The regulators and downstream targets of Rab3A have been isolated, and evidence is accumulating that Rab3A and these Rab3A-interacting proteins are involved in Ca2+-dependent exocytosis, particularly in neurotransmitter release from nerve terminals.
引用
收藏
页码:615 / 632
页数:18
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