The clinical features of Sjogren's syndrome in Japanese children

被引：0
|
作者：
Tomiita, M
Saito, K
Kohno, Y
Shimojo, N
Fujikawa, S
Niimi, H
机构：
[1] SOCIAL INSURANCE FUNABASHI CENT HOSP, DEPT PEDIAT, FUNABASHI, CHIBA, JAPAN
[2] DOKKYO UNIV, KOSHIGAYA HOSP, DEPT PEDIAT, SCH MED, KOSHIGAYA, JAPAN
来源：
ACTA PAEDIATRICA JAPONICA | 1997年 / 39卷 / 02期
关键词：
children; Japan; Sjogren's syndrome;
D O I：
暂无
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Sjogren's syndrome (SS) is thought to be uncommon in children. An epidemiological study to describe the clinical features distinguishing SS in Japanese children was performed by sending questionnaires to hospitals. A total of 61 cases of SS were reported from 1290 hospitals. The diagnosis of SS was based on histopathological changes and/or sialographic changes in the salivary glands, Forty-two cases had prim,sly SS and 19 were secondary SS with other autoimmune disorders. Fourteen cases (65%) of secondary SS were associated with systemic lupus erythematosus. In primary SSI the initial symptoms were systemic manifestations (fever, exanthema arthralgia. etc) except for sicca symptoms, In laboratory studies, antinuclear antibodies, elevated serum Igc. rheumatoid factor, anti-Ro/SS-A antibodies and anti-La!SS-B antibodies were frequently observed.
引用
收藏
页码：268 / 272
页数：5
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