Miniature spectrometers for biochemical analysis

被引:72
|
作者
Yee, GM
Maluf, NI
Hing, PA
Albin, M
Kovacs, GTA
机构
[1] LUCAS NOVASENSOR,FREMONT,CA 94539
[2] PE APPL BIOSYST,FOSTER CITY,CA 94404
基金
美国国家科学基金会;
关键词
biochemical analysis; micromachining; miniature spectrometers;
D O I
10.1016/S0924-4247(97)80225-7
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Miniature spectrometers have been demonstrated by mounting micromachined diffraction gratings onto CCD imaging devices. Two implementations are tested: one for high-dispersion and -sensitivity applications, and the other for low-cost consumer applications. The first system shows a dispersion of 1.7 nm/pixel and a resolution of 74.4 for the bandwidth of interest. The free spectral range of the device is designed to be in the visible range for this particular application. The diffraction efficiency of the system is 63%. The second, low-cost system demonstrates a dispersion and resolution of 2.55 nm/pixel and 69.8, respectively. These specifications are comparable to that of a conventional, low-end commercial spectrometer. Results are shown for their applications in biochemical analysis. Further optimization is sought by adding micromachined lenses and creating specialized, computer-generated gratings to compress and shape the spectral signal.
引用
收藏
页码:61 / 66
页数:6
相关论文
共 50 条
  • [1] Miniature spectrometers for biochemical analysis
    Yee, GM
    Maluf, NI
    Hing, PA
    Albin, M
    Kovacs, GTA
    MICRO- AND NANOFABRICATED ELECTRO-OPTICAL MECHANICAL SYSTEMS FOR BIOMEDICAL AND ENVIRONMENTAL APPLICATIONS, PROCEEDINGS OF, 1997, 2978 : 75 - 81
  • [2] Miniature spectrometers
    Sherma, J
    Larkin, JD
    Larkin, FH
    JOURNAL OF AOAC INTERNATIONAL, 2003, 86 (03) : 47A - 52A
  • [3] Development of Miniature Spectrometers
    ZHANG Zhi-guo (The Educational Administration of Beihua University
    SemiconductorPhotonicsandTechnology, 2007, (02) : 132 - 135
  • [4] Miniature Mass Spectrometers
    Ouyang, Zheng
    Cooks, R. Graham
    ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, 2009, 2 : 187 - 214
  • [5] MINIATURE MASS SPECTROMETERS FOR ON-SITE CHEMICAL ANALYSIS
    Zhou, Xiaoyu
    Li, Shuai
    Ouyang, Zheng
    2023 IEEE 36TH INTERNATIONAL VACUUM NANOELECTRONICS CONFERENCE, IVNC, 2023, : 157 - 159
  • [6] High-performance miniature integrated infrared spectrometers for industrial and biochemical sensing.
    Kruzelecky, RV
    Ghosh, AK
    ADVANCED ENVIRONMENTAL AND CHEMICAL SENSING TECHNOLOGY, 2001, 4205 : 25 - 34
  • [7] Miniature mass spectrometers and their potential for clinical point-of-care analysis
    Zhai, Yanbing
    Fu, Xinyan
    Xu, Wei
    MASS SPECTROMETRY REVIEWS, 2024, 43 (05) : 1172 - 1191
  • [8] Optical probe systems for miniature spectrometers
    Nikolov, ID
    OPTIKA '98 - 5TH CONGRESS ON MODERN OPTICS, 1998, 3573 : 376 - 379
  • [9] Miniature spectrometers for planetary remote sensing
    Scott, A
    Rowlands, N
    Bell, A
    INSTRUMENTS, SCIENCE, AND METHODS FOR GEOSPACE AND PLANETARY REMOTE SENSING, 2004, 5660 : 78 - 87