Epidemiology of Head and Neck Cancer

被引:346
|
作者
Rettig, Eleni M. [1 ]
D'Souza, Gypsyamber [2 ]
机构
[1] Johns Hopkins Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Baltimore, MD 21287 USA
[2] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA
关键词
Head and neck cancer; Tobacco; Human papillomavirus; Alcohol; Epidemiology; SQUAMOUS-CELL CARCINOMA; ORAL HUMAN-PAPILLOMAVIRUS; UPPER AERODIGESTIVE TRACT; OROPHARYNGEAL CANCER; HPV INFECTION; UNITED-STATES; RISK-FACTORS; TRANSPLANT RECIPIENTS; CIGARETTE-SMOKING; ALCOHOL-DRINKING;
D O I
10.1016/j.soc.2015.03.001
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This article discusses risk factors, incidence trends, and prognostic considerations for head and neck cancer (HNC). The primary causes of HNC are tobacco and alcohol use, and human papillomavirus (HPV). Tobacco-related HNC incidence rates are decreasing in countries where tobacco use has declined. HPV-HNC, which occurs primarily in the oropharynx and is associated with sexual behaviors, has been increasing over the past several decades, among white men in particular. The prognosis for HNC overall has improved slightly since the 1990s, and is influenced by site, stage, and HPV status. Prognosis for HPV-HNC is significantly better than for HPV-negative disease.
引用
收藏
页码:379 / +
页数:19
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