Cognitive-Behavioural Correlates of Dysbiosis: A Review

被引：19
|
作者：
Luca, Maria [1 ]
Chattipakorn, Siriporn C. [2 ,3 ,4 ]
Sriwichaiin, Sirawit [2 ,3 ,5 ]
Luca, Antonina [1 ]
机构：
[1] GF Ingrassia Univ Catania, Dept Med & Surg Sci & Adv Technol, I-95123 Catania, Italy
[2] Chiang Mai Univ, Fac Med, Cardiac Electrophysiol Res & Training Ctr, Neurophysiol Unit, Chiang Mai 50200, Thailand
[3] Chiang Mai Univ, Ctr Excellence Cardiac Electrophysiol Res, Chiang Mai 50200, Thailand
[4] Chiang Mai Univ, Fac Dent, Dept Oral Biol & Diagnost Sci, Chiang Mai 50200, Thailand
[5] Chiang Mai Univ, Fac Med, Dept Physiol, Cardiac Electrophysiol Unit, Chiang Mai 50200, Thailand
来源：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2020年 / 21卷 / 14期
关键词：
microbiota; gut; dysbiosis; behaviour; cognition; CHAIN FATTY-ACIDS; GUT MICROBIOTA; INTESTINAL BACTERIA; SCHIZOPHRENIA; STRESS; METAANALYSIS; INFECTION; LACTOBACILLUS; METABOLISM; DEPRESSION;
D O I：
10.3390/ijms21144834
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Evidence suggests an association between an altered gut microbiota (dysbiosis), cognitive performance and behaviour. This paper provides an overview of the current literature regarding the cognitive-behavioural correlates of dysbiosis, with special attention on the clinical and biochemical mechanisms underlying the association between dysbiosis, cognition (mild cognitive impairment and dementia) and behaviour (depression, schizophrenia, addiction). After providing an overview of the evidence, the review discusses the molecular aspects that could account for the cognitive-behavioural correlates of dysbiosis. Shedding light on this topic could provide insights regarding the pathogenesis of these burdening neuropsychiatric disorders and even suggest future therapeutic strategies.
引用
收藏
页码：1 / 14
页数：14
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