Comparison of Phacotrabeculectomy and Phacotrabeculectomy with Subconjunctival 5-Fluorouracil

Introduction: Glaucoma is the second leading cause of blindness worldwide. Phacotrabeculectomy is a technique in which glaucoma and cataract surgery performed. Methods: Prospective study was carried out in the department of glaucoma at Lumbini Eye Institute, Bhairahawa. 100 patients who underwent phacotrabeculectomy within a period of two years. Patients were divided into two groups those who received 5FU (n=47) and no antifibrotic agent (n=53) Results: The age range was from 38 to 80 years; mean age of 62.97+/-9.14 SD. 55% were male and 45% were female. The postoperative IOP reduction in last follow-up group A was mean=13.08+/-1.57SD and mean=13.23+/-1.73SD in group B. This was statically significant with P <0.001. Bleb survival was almost similar in two groups 3.17(78.31%) in group A and 3.20 (78.93%) in group B. 85% visual acuity was improved in both groups. Conclusions: Phacotrabeculectomy and phacotrabeculectomy with inj. 5FU, both were equally effective surgical techniques in terms of visual acuity, IOP control and bleb survival. There was no significant statistical difference vis-a-vis the success of Phacotrabeculectomy using of either these two techniques.