Detection of low-frequent desmoglein 3-specific T and B cells in an HLA transgenic mouse model of pemphigus vulgaris

被引：0
|
作者：
Hudemann, C. [1 ]
Pollmann, R. [1 ]
Hertl, M. [1 ]
Fleischer, S. [2 ]
Eming, R. [1 ]
机构：
[1] Philipps Univ Marburg, D-35043 Marburg, Germany
[2] Topas Therapeut GmbH, D-20251 Hamburg, Germany
来源：
EXPERIMENTAL DERMATOLOGY | 2019年 / 28卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
P155
引用
收藏
页码：E74 / E74
页数：1
相关论文
共 50 条
  • [1] Induction of desmoglein 3-specific T cell tolerance in a mouse model of pemphigus vulgaris
    Hudemann, C.
    Hertl, M.
    Fleischer, S.
    Digigow, R.
    Eming, R.
    [J]. EXPERIMENTAL DERMATOLOGY, 2023, 32 (04) : E79 - E79
  • [2] Desmoglein 3-specific antibodies generated in an HLA-class II-transgenic mouse model of pemphigus vulgaris are pathogenic
    Eming, R.
    Feliciani, C.
    Eubel, V.
    Podstawa, E.
    Mueller, R.
    Sonderstrup, G.
    Hertl, M.
    [J]. EXPERIMENTAL DERMATOLOGY, 2008, 17 (03) : 253 - 253
  • [3] T-B cell interaction is crucial for the induction of desmoglein 3-specific IgG autoantibodies in an HLA-class II transgenic mouse model of pemphigus vulgaris
    Eming, R.
    Hertl, M.
    Schmidt, J.
    Podstawa, E.
    Feliciani, C.
    Sonderstrup, G.
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2007, 127 : S66 - S66
  • [4] Analysis of autoreactive desmoglein 3-specific B cells in patients with pemphigus vulgaris
    Pollmann, R.
    Schmidt, T.
    Moebs, C.
    Pfuetzner, W.
    Hertl, M.
    Eming, R.
    [J]. EXPERIMENTAL DERMATOLOGY, 2017, 26 (03) : E69 - E69
  • [5] A Humanized HLA-class II transgenic mouse model for the analysis of desmocollin 3-specific T - and B cell responses in pemphigus
    Llamazares, M.
    Spoetzl, S.
    Karlmark, K. R.
    Hertl, M.
    Eming, R.
    [J]. EXPERIMENTAL DERMATOLOGY, 2012, 21 (03) : e20 - e20
  • [6] HLA-class II-restricted activation of desmoglein 3-specific CD4+T cells is required for the formation of pathogenic antibodies in a mouse model of pemphigus vulgaris
    Eming, R.
    Hennerici, T.
    Backlund, J.
    Feliciani, C.
    Visconti, K.
    Willenborg, S.
    Wohde, J.
    Holmdahl, R.
    Sonderstrup, G.
    Herti, M.
    [J]. EXPERIMENTAL DERMATOLOGY, 2014, 23 : 10 - 10
  • [7] Desmoglein 3-specific CD4+ T cells induce pemphigus vulgaris and interface dermatitis in mice
    Takahashi, Hayato
    Kouno, Michiyoshi
    Nagao, Keisuke
    Wada, Naoko
    Hata, Tsuyoshi
    Nishimoto, Shuhei
    Iwakura, Yoichiro
    Yoshimura, Akihiko
    Yamada, Taketo
    Kuwana, Masataka
    Fujii, Hideki
    Koyasu, Shigeo
    Amagai, Masayuki
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2011, 121 (09): : 3677 - 3688
  • [8] Ex vivo analysis of T cell epitopes of desmoglein 3 in a HLA class II-transgenic mouse model of Pemphigus vulgaris
    Eming, R
    Schmidt, J
    Visconti, KC
    Sonderstrup, G
    Hertl, M
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2005, 125 (03) : A12 - A12
  • [9] High-dose immunoglobulins induce T regulatory (Treg) cells which downregulate desmoglein 3-specific IgG antibodies in a human leukocyte antigen-transgenic mouse model of pemphigus vulgaris
    Eming, R.
    Schimo, S.
    Rentz, E.
    Hertl, M.
    Hudemann, C.
    [J]. EXPERIMENTAL DERMATOLOGY, 2021, 30 (03) : E51 - E51
  • [10] High-dose immunoglobulins induce a reduction of desmoglein 3-specific IgG antibodies in a human leukocyte antigen-transgenic mouse model of pemphigus vulgaris.
    Lee, J. H.
    Pollmann, R.
    Hudemann, C.
    Rentz, E.
    Hertl, M.
    Eming, R.
    [J]. EXPERIMENTAL DERMATOLOGY, 2018, 27 (03) : E68 - E68
12345