The Nicholas-type activation of cyclopropanes toward reactions with nitrones in the homo-[3+2]-dipolar cycloaddition

被引：30
|
作者：
Lebold, TP [1 ]
Carson, CA [1 ]
Kerr, MA [1 ]
机构：
[1] Univ Western Ontario, Dept Chem, London, ON N6A 5B7, Canada
来源：
SYNLETT | 2006年 / 03期
关键词：
tetrahydro-1,2-oxazine; cycloaddition; cyclopropanes; Pauson-Khand;
D O I：
10.1055/s-2006-926240
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
2-Ethynyl-1,1-carboethoxyclopropane, when treated with Co-2(CO)(8), results in the formation of the Co-2(CO)(6) adduct which in turn undergoes smooth cycloaddition in the presence of Sc(OTf)(3) to form the corresponding tetrahdyro-1,2-oxazines. The adducts can either be decomplexed to yield the parent acetylenes or made to undergo Pauson-Khand reactions to form 6-cyclopentenyltetrahydro-1,2-oxazines.
引用
收藏
页码：364 / 368
页数：5
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