Complete Genome Sequence Analysis of a Newcastle Disease Virus Isolated from a Wild Egret

被引:18
|
作者
Xie, Zhixun [1 ]
Xie, Liji [1 ]
Chen, Anli [1 ]
Liu, Jiabo [1 ]
Pang, Yaoshan [1 ]
Deng, Xianwen [1 ]
Xie, Zhiqin [1 ]
Fan, Qing [1 ]
机构
[1] Guangxi Vet Res Inst, Guangxi Key Lab Anim Vaccines & Diagnost, Nanning, Guangxi Provinc, Peoples R China
关键词
FUSION PROTEIN; CLEAVAGE SITE; VIRULENCE;
D O I
10.1128/JVI.02669-12
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We report here the complete genomic sequence of a novel Newcastle disease virus (NDV) strain, egret/China/Guangxi/2011, isolated from an egret in Guangxi Province, southern China. A phylogenetic analysis based on a fusion gene comparison with different NDV strains revealed that egret/China/Guangxi/2011 was phylogenetically close to genotype VIIa NDV, and the deduced amino acid sequence was R-112-R-R-K-R-F-117 at the fusion protein cleavage site. The whole nucleotide sequence had the highest homology (93.3%) with the sequence of strain chicken/Sukorejo/019/10 (GenBank accession number HQ697255). This study will help us to understand the epidemiology and molecular characteristics of Newcastle disease virus in a migratory egret.
引用
收藏
页码:13854 / 13855
页数:2
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