The synthesis of fluorine-containing pterins

被引：9

作者：

Dunn, C ^{[1
]}

Gibson, CL ^{[1
]}

Suckling, CJ ^{[1
]}

机构：

[1] UNIV STRATHCLYDE, DEPT PURE & APPL CHEM, GLASGOW G1 1XL, LANARK, SCOTLAND

来源：

TETRAHEDRON | 1996年 / 52卷 / 40期

关键词：

D O I：

10.1016/0040-4020(96)00782-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of some 7,7-difluoro-7,8-digydropterins and pterins with fluoroalkyl subsitutents at the 6 or 7 positions from fluorine-containing aliphatic precursors and suitably substituted pyrimidines is described. The fluorine-containing pterins were found to be very insoluble and also stable to nucleophiles and bases in dilute aqueous solution. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：13017 / 13026

页数：10

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