Targeted Genomic Profiling Reveals Highly Recurrent Molecular Alterations in the Malignant Progression of Sinonasal Papilloma to Sinonasal Squamous Cell Carcinoma, including CDKN2A Mutation/Deletion and TP53 Mutation

被引:0
|
作者
Yilmaz, Osman [1 ]
Kunder, Komal [1 ]
McHugh, Jonathan [2 ]
Betz, Bryan L. [3 ]
Tomlins, Scott [1 ]
Brown, Noah [1 ]
Udager, Aaron M. [3 ]
机构
[1] Univ Michigan, Ann Arbor, MI 48109 USA
[2] Univ Michigan Hlth Syst, Ann Arbor, MI USA
[3] Univ Michigan, Med Sch, Ann Arbor, MI 48109 USA
关键词
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
1384
引用
收藏
页码:492 / 492
页数:1
相关论文
共 18 条
  • [1] Targeted Genomic Profiling Reveals Highly Recurrent Molecular Alterations in the Malignant Progression of Sinonasal Papilloma to Sinonasal Squamous Cell Carcinoma, including CDKN2A Mutation/Deletion and TP53 Mutation
    Yilmaz, Osman
    Kunder, Komal
    McHugh, Jonathan
    Betz, Bryan L.
    Tomlins, Scott
    Brown, Noah
    Udager, Aaron M.
    MODERN PATHOLOGY, 2018, 31 : 492 - 492
  • [2] TP53 mutations and CDKN2A mutations/deletions are highly recurrent molecular alterations in the malignant progression of sinonasal papillomas
    Brown, Noah A.
    Plouffe, Komal R.
    Yilmaz, Osman
    Weindorf, Steven C.
    Betz, Bryan L.
    Carey, Thomas E.
    Seethala, Raja R.
    McHugh, Jonathan B.
    Tomlins, Scott A.
    Udager, Aaron M.
    MODERN PATHOLOGY, 2021, 34 (06) : 1133 - 1142
  • [3] Assessment of TP53 and CDKN2A status can be a predictive marker of malignant transformation of sinonasal inverted papilloma
    Kwon, S.
    Kim, E. S.
    Paik, J. H.
    Chung, J.
    Wee, J. H.
    Cho, S.
    Won, T.
    Kim, J.
    Rhee, C. S.
    Kim, H.
    VIRCHOWS ARCHIV, 2022, 481 (SUPPL 1) : S71 - S71
  • [4] Assessment of TP53 and CDKN2A status as predictive markers of malignant transformation of sinonasal inverted papilloma (vol 14, 14286, 2024)
    Kwon, Soohyeon
    Kim, Jeong-Whun
    Kim, Eun Sun
    Paik, Jin Ho
    Chung, Jin-Haeng
    Cho, Sung-Woo
    Won, Tae-Bin
    Rhee, Chae-Seo
    Wee, Jee Hye
    Kim, Hyojin
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [5] Whole Exome Sequencing Revealed that Assessment of TP53 and CDKN2A Status can be a Predictive Marker of Malignant Transformation of Sinonasal Inverted Papilloma
    Kwon, Soohyeon
    Wee, Jee Hye
    Kim, Hyojin
    MODERN PATHOLOGY, 2022, 35 (SUPPL 2) : 884 - 885
  • [6] Whole Exome Sequencing Revealed that Assessment of TP53 and CDKN2A Status can be a Predictive Marker of Malignant Transformation of Sinonasal Inverted Papilloma
    Kwon, Soohyeon
    Wee, Jee Hye
    Kim, Hyojin
    LABORATORY INVESTIGATION, 2022, 102 (SUPPL 1) : 884 - 885
  • [7] Targeted Genomic Profiling of BRAF/KIT/NRAS Mutation-Negative Gynecologic Melanoma Reveals Recurrent NF1 Alterations and TP53 Mutations
    Carter, Cody
    Kunder, Komal
    Andea, Aleodor
    Chan, May P.
    Fullen, Douglas
    Lowe, Lori
    Tomlins, Scott
    Udager, Aaron M.
    Patel, Rajiv
    LABORATORY INVESTIGATION, 2018, 98 : 410 - 411
  • [8] Targeted Genomic Profiling of BRAF/KIT/NRAS Mutation-Negative Gynecologic Melanoma Reveals Recurrent NF1 Alterations and TP53 Mutations
    Carter, Cody
    Kunder, Komal
    Andea, Aleodor
    Chan, May P.
    Fullen, Douglas
    Lowe, Lori
    Tomlins, Scott
    Udager, Aaron M.
    Patel, Rajiv
    MODERN PATHOLOGY, 2018, 31 : 410 - 411
  • [9] Correlation of tumor mutational burden (TMB) with CDKN2A and TP53 mutation in HPV-negative head and neck squamous cell carcinoma (HNSCC).
    Burtness, Barbara
    Deneka, Alexander
    Baca, Yasmine
    Serebriiskii, Ilya
    Parker, Mitchell, I
    Nicolas, Emmanuelle
    Lee, Jong Woo
    Wise-Draper, Trisha
    Sukari, Ammar
    Somer, Bradley G.
    Golemis, Erica
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [10] Co-Occurrence of TP53 and CDKN2A Genomic Alterations is Less Common in HPV-Associated Squamous Cell Carcinomas
    Modi, Lopa
    Kuwadekar, Aditya S.
    Balshan, Eli
    Zhong, Hua
    MODERN PATHOLOGY, 2018, 31 : 704 - 704