Fibre-optic interferometric immuno-sensor using long period grating

被引：52
|
作者：
Kim, DW [1 ]
Zhang, Y [1 ]
Cooper, KL [1 ]
Wang, A [1 ]
机构：
[1] Virginia Polytech Inst & State Univ, Bradley Dept Elect & Comp Engn, Ctr Photon Technol, Blacksburg, VA 24061 USA
来源：
ELECTRONICS LETTERS | 2006年 / 42卷 / 06期
关键词：
D O I：
10.1049/el:20060040
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
A species-specific biosensor is presented based on the combined use of a reflection mode long period fibre grating with nanoscale self-assembly. Self-assembled polyelectrolyte layers and the immobilisation of immunoglobulin G (IgG) were used for sensor fabrication. The sensor's fringe position shift induced by specific antigen-antibody binding has been observed, and non-specific binding was minimised with binding block. The results show the feasibility of the sensor for various bio/chemical applications.
引用
收藏
页码：324 / 325
页数：2
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