Protein adsorption on heterogeneous surfaces

被引：14

作者：

Aggarwal, Nitesh ^{[1
,2
]}

Lawson, Ken ^{[1
]}

Kershaw, Matthew ^{[1
]}

Horvath, Robert ^{[1
]}

Ramsden, Jeremy ^{[1
]}

机构：

[1] Cranfield Univ, Dept Mat, Cranfield MK43 0AL, Beds, England

[2] Indian Inst Technol, Dept Met Engn & Mat Sci, Bombay 400076, Maharashtra, India

来源：

APPLIED PHYSICS LETTERS | 2009年 / 94卷 / 08期

关键词：

adsorption; biomedical materials; blood; proteins; silicon compounds; zirconium compounds; RANDOM SEQUENTIAL ADSORPTION; SERUM-ALBUMIN ADSORPTION; MODEL;

D O I：

10.1063/1.3078397

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

The adsorption of the protein bovine serum albumin from an aqueous solution onto substrata made from pure silica, pure zirconia, and a mixture of the two has revealed that the adsorption behavior of the protein onto the mixture very significantly diverges from the corresponding mean of the behaviors with the pure substrata. A tentative explanation in terms of matching substratum heterogeneity with protein surface heterogeneity is offered.

引用

页数：3

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