Recombination Is Associated with an Outbreak of Novel Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Viruses in China

被引:77
|
作者
Shi, Mang [1 ,2 ]
Holmes, Edward C. [1 ,2 ,3 ]
Brar, Manreetpal Singh [4 ]
Leung, Frederick Chi-Ching [4 ,5 ]
机构
[1] Univ Sydney, Sch Biol Sci, Sydney Emerging Infect & Biosecur Inst, Sydney, NSW 2006, Australia
[2] Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia
[3] NIH, Fogarty Int Ctr, Bethesda, MD 20892 USA
[4] Univ Hong Kong, Sch Biol Sci, Hong Kong, Hong Kong, Peoples R China
[5] Nanjing Agr Univ, Bioinformat Ctr, Nanjing, Jiangsu, Peoples R China
基金
澳大利亚国家健康与医学研究理事会;
关键词
D O I
10.1128/JVI.01270-13
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In 2009 to 2010, there was a marked increase in the number of infections with highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) in China. Through phylogenetic analysis, we show that viruses from this outbreak originated from a single recombination event, illustrating the potential importance of this process for disease emergence.
引用
收藏
页码:10904 / 10907
页数:4
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