melanoma;
reconstruction;
timing;
immediate;
margin;
head and neck;
PROGNOSTIC-FACTORS;
SURGICAL-MANAGEMENT;
LOCAL RECURRENCE;
STAGING SYSTEM;
DELAYED REPAIR;
EXCISION;
THICKNESS;
RESECTION;
D O I:
10.1097/SAP.0b013e31817dadc8
中图分类号:
R61 [外科手术学];
学科分类号:
摘要:
Head and neck melanoma often approaches critical structures. Therefore, excision is often limited, leading to positive margins, and increased local recurrence. Immediate reconstruction carries concern for rearrangement or concealment of cancerous tissues. Therefore, reconstruction is often delayed until confirming negative margins on permanent pathology. Our purpose is to identify variables associated with a positive margin and establish criteria for reconstruction timing. We reviewed 117 consecutive patients who underwent wide local excision of head and neck melanoma. Reconstruction was immediate for 107 and delayed for 10. Six percent of patients had a positive margin after wide local excision with no difference in incidence between immediate and delayed reconstruction (P = 0.11). Tumor characteristics associated with a positive mar-in were locally recurrent, ulcerated, and T4 tumors (P < 0.05); and delayed reconstruction should be considered in these circumstances. Immediate reconstruction is safe for the majority of head and neck melanoma and should be based on knowledge of tumor characteristics.
机构:
Univ Calif Irvine, Dept Plast Surg, 200 S Manchester Ave Suite 650, Orange, CA 92868 USAUniv Calif Irvine, Dept Plast Surg, 200 S Manchester Ave Suite 650, Orange, CA 92868 USA
Hu, Allison C.
Lee, Seung Ah
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h-index: 0
机构:
Univ Calif Irvine, Dept Plast Surg, 200 S Manchester Ave Suite 650, Orange, CA 92868 USAUniv Calif Irvine, Dept Plast Surg, 200 S Manchester Ave Suite 650, Orange, CA 92868 USA
Lee, Seung Ah
Clark, Emily G.
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机构:
Univ Calif Irvine, Dept Plast Surg, 200 S Manchester Ave Suite 650, Orange, CA 92868 USAUniv Calif Irvine, Dept Plast Surg, 200 S Manchester Ave Suite 650, Orange, CA 92868 USA
Clark, Emily G.
Yamamoto, Maki
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h-index: 0
机构:
Univ Calif Irvine, Dept Surg, Div Surg Oncol, Orange, CA 92668 USAUniv Calif Irvine, Dept Plast Surg, 200 S Manchester Ave Suite 650, Orange, CA 92868 USA
Yamamoto, Maki
Jakowatz, James G.
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h-index: 0
机构:
Univ Calif Irvine, Dept Surg, Div Surg Oncol, Orange, CA 92668 USAUniv Calif Irvine, Dept Plast Surg, 200 S Manchester Ave Suite 650, Orange, CA 92868 USA
Jakowatz, James G.
Evans, Gregory R. D.
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h-index: 0
机构:
Univ Calif Irvine, Dept Plast Surg, 200 S Manchester Ave Suite 650, Orange, CA 92868 USAUniv Calif Irvine, Dept Plast Surg, 200 S Manchester Ave Suite 650, Orange, CA 92868 USA
机构:
Brown Univ, Warren Alpert Med Sch, Div Plast & Reconstruct Surg, Providence, RI 02905 USA
Rhode Isl Hosp, Dept Plast & Reconstruct Surg, Providence, RI USA
Hasbro Childrens Hosp, Providence, RI USABrown Univ, Warren Alpert Med Sch, Div Plast & Reconstruct Surg, Providence, RI 02905 USA
Sullivan, Stephen R.
Liu, Daniel Z.
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h-index: 0
机构:
Univ Washington, Div Plast & Reconstruct Surg, Seattle, WA 98195 USABrown Univ, Warren Alpert Med Sch, Div Plast & Reconstruct Surg, Providence, RI 02905 USA
Liu, Daniel Z.
Mathes, David W.
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h-index: 0
机构:
Univ Washington, Div Plast & Reconstruct Surg, Seattle, WA 98195 USABrown Univ, Warren Alpert Med Sch, Div Plast & Reconstruct Surg, Providence, RI 02905 USA
Mathes, David W.
Isik, F. Frank
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h-index: 0
机构:
The Polyclinic, Seattle, WA USABrown Univ, Warren Alpert Med Sch, Div Plast & Reconstruct Surg, Providence, RI 02905 USA