Cardiopulmonary interactions during mechanical ventilation in critically ill patients

被引:31
|
作者
Cherpanath, T. G. V. [1 ]
Lagrand, W. K. [1 ]
Schultz, M. J. [2 ]
Groeneveld, A. B. J. [3 ]
机构
[1] Univ Amsterdam, Acad Med Ctr, Dept Intens Care Med, NL-1105 AZ Amsterdam, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, Lab Expt Intens Care & Anesthesiol, Dept Intens Care Med, NL-1105 AZ Amsterdam, Netherlands
[3] Erasmus MC, Dept Intens Care Med, NL-3015 CE Rotterdam, Netherlands
关键词
Mechanical ventilation; Preload; Afterload; Positive pressure ventilation; Cardiopulmonary interaction; RESPIRATORY-DISTRESS-SYNDROME; END-EXPIRATORY PRESSURE; ACUTE LUNG INJURY; VENTRICULAR OUTFLOW IMPEDANCE; STROKE VOLUME VARIATION; LOWER TIDAL VOLUMES; PROTECTIVE VENTILATION; CLINICAL-IMPLICATIONS; FLUID RESPONSIVENESS; ARTERIAL-PRESSURE;
D O I
10.1007/s12471-013-0383-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiopulmonary interactions induced by mechanical ventilation are complex and only partly understood. Applied tidal volumes and/or airway pressures largely mediate changes in right ventricular preload and afterload. Effects on left ventricular function are mostly secondary to changes in right ventricular loading conditions. It is imperative to dissect the several causes of haemodynamic compromise during mechanical ventilation as undiagnosed ventricular dysfunction may contribute to morbidity and mortality.
引用
收藏
页码:166 / 172
页数:7
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