A Surface Plasmon Resonance Biochip That Operates Both in the Angular and Wavelength Interrogation Modes

被引：33
|
作者：
Oliveira, Leiva Casemiro [1 ]
Moreira, Cleumar da Silva [2 ]
Thirstrup, Carsten [3 ]
Kurt Melcher, Elmar Uwe [4 ,5 ]
Nogueira Lima, Antonio Marcus [1 ]
Neff, Helmut [1 ,5 ]
机构：
[1] Univ Fed Campina Grande, Dept Elect Engn, BR-58109900 Campina Grande, PB, Brazil
[2] Inst Fed Alagoas, Dept Elect, Maceio, AL, Brazil
[3] Danish Fundamental Metrol, Copenhagen, Denmark
[4] Univ Fed Campina Grande, Dept Comp Sci, BR-58109900 Campina Grande, PB, Brazil
[5] Northeast Ctr Strateg Technol, Recife, PE, Brazil
来源：
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT | 2013年 / 62卷 / 05期
关键词：
Biomedical transducers; optical spectroscopy; optical transducers; optoelectronic devices; plasmons; thin-film devices; BIOSENSOR; PERFORMANCE; SENSOR; CHIP;
D O I：
10.1109/TIM.2012.2232433
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
This paper presents a surface plasmon resonance system based on a polymer prism chip. The device allows operation in both the angular and wavelength interrogation modes. The biochip design is discussed emphasizing the effect of the ambient temperature over the optical behavior. Birefringence effect, biochip polishing, and responsivity are also reported. The basic mathematical formulation for both operating modes is discussed, and morphological parameters are considered in the data analysis. Experimental sensorgrams obtained at both interrogation modes with the same polymer prism chip are presented and compared. The experimental sensorgrams obtained with assays providing reversible (phosphate buffered saline and hypochlorite solutions) and irreversible (neutravindin solution) bindings demonstrate the feasibility of the proposed design.
引用
收藏
页码：1223 / 1232
页数：10
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