A Case Study of Zoonotic Chlamydia abortus Infection: Diagnostic Challenges From Clinical and Microbiological Perspectives

被引：11

作者：

Burgener, Anne-Valerie ^{[1
]}

Seth-Smith, Helena M. B. ^{[2
,3
]}

Kern-Baumann, Sina ^{[4
]}

Durovic, Ana ^{[1
]}

Blaich, Anette ^{[2
]}

Menter, Thomas ^{[5
]}

Bruder, Elisabeth ^{[5
]}

Roloff, Tim ^{[2
,3
]}

Martinez, Aurelien ^{[1
]}

Borel, Nicole ^{[6
]}

Albini, Sarah ^{[7
]}

Hosli, Irene ^{[4
]}

Egli, Adrian ^{[2
,3
]}

Weisser, Maja ^{[1
]}

Hinic, Vladimira ^{[2
]}

机构：

[1] Univ Hosp Basel, Div Infect Dis & Hosp Epidemiol, Petersgraben 4, CH-4031 Basel, Switzerland

[2] Univ Hosp Basel, Div Clin Bacteriol & Mycol, Basel, Switzerland

[3] Univ Basel, Dept Biomed, Appl Microbiol Res, Basel, Switzerland

[4] Univ Hosp Basel, Dept Obstet, Basel, Switzerland

[5] Univ Hosp Basel, Inst Med Genet & Pathol, Basel, Switzerland

[6] Univ Zurich, Vetsuisse Fac, Inst Vet Pathol, Zurich, Switzerland

[7] Univ Zurich, Vetsuisse Fac, Natl Reference Ctr Poultry & Rabbit Dis, Inst Food Safety & Hyg, Zurich, Switzerland

来源：

OPEN FORUM INFECTIOUS DISEASES | 2022年 / 9卷 / 10期

关键词：

abortion; Chlamydia abortus; pregnancy; sequencing; zoonosis; doxycycline; PREGNANT-WOMAN; PSITTACOSIS; SHEEP; TIME; RISK; PCR;

D O I：

10.1093/ofid/ofac524

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Chlamydia abortus is the most common causative agent of abortion in small ruminants, but it is poorly recognized as a human pathogen. In most published case studies, diagnosis remained difficult and often resulted in delayed initiation of therapy. In this case study of severe C abortus infection in a pregnant farmer from Switzerland, we highlight the clinical and microbiological diagnostic challenges and provide evidence of a zoonotic epidemiological link.

引用

页数：5

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