Controlled-folding of a small molecule modulates DNA G-quadruplex recognition

被引:25
|
作者
Mueller, Sebastian [1 ]
Pantos, G. Dan [1 ]
Rodriguez, Raphael [1 ]
Balasubramanian, Shankar [1 ]
机构
[1] Univ Cambridge, Univ Chem Lab, Cambridge CB2 1EW, England
关键词
C-KIT ONCOGENE; BINDING LIGANDS; TRANSCRIPTION; MACROCYCLES; DERIVATIVES; INHIBITION; TELOMERASE; PORPHYRIN; PROMOTER; MYC;
D O I
10.1039/b816861j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Differential recognition of diverse G-quadruplex structures can be achieved by controlling the folding of a small molecule.
引用
收藏
页码:80 / 82
页数:3
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