Performance characteristics of microparticle enzyme and chemiluminescence immunoassays for measurement of anti-HBc immunoglobulin M in sera of patients with HBeAg-negative chronic hepatitis B virus infection

被引：2
|
作者：
Hadziyannis, Emilia [1 ]
Manesis, Emanuel [1 ]
Vassilopoulos, Dimitrios [1 ]
Georgiou, Anastasia [1 ]
Archimandritis, Athanasios [1 ]
机构：
[1] Univ Athens, Sch Med, Hippokrat Gen Hosp, Acad Dept Med, GR-11527 Athens, Greece
来源：
CLINICAL AND VACCINE IMMUNOLOGY | 2008年 / 15卷 / 02期
关键词：
D O I：
10.1128/CVI.00414-07
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The IMx, AxSym, and Architect immunoglobulin M anti-HBc assay systems for detecting hepatitis B virus e antigen-negative chronic hepatitis B virus infection were compared. Despite good intra- and interassay coefficients of variation, significantly different values and low correlation (overestimation by AxSym and underestimation by Architect) were observed. Association and cutoff values for distinguishing patients with viral replication should be established for all methods.
引用
收藏
页码：385 / 387
页数：3
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