Fabrication and characterization of step-index biocompatible and biodegradable polyesters based optical fiber

被引:2
|
作者
Gierej, Agnieszka [1 ]
Filipkowski, Adam [2 ]
Pysz, Dariusz [2 ]
Buczynski, Ryszard [2 ]
Vagenende, Maxime [1 ,3 ]
Van Vlierberghe, Sandra [3 ]
Dubruel, Peter [3 ]
Thienpont, Hugo [1 ]
Geernaert, Thomas [1 ]
Berghmans, Francis [1 ]
机构
[1] Vrije Univ Brussel, Dept Appl Phys & Photon, Brussels Photon B PHOT, Pl Laan 2, B-1050 Brussels, Belgium
[2] Lukasiewicz Inst Elect Mat Technol ITME, 133 Wolczynska Str, PL-01919 Warsaw, Poland
[3] Ctr Macromol Chem CMaC, Dept Organ & Macromol Chem, Polymer Chem & Biomat Grp PBM, Krijgslaan 281 S4bis, B-9000 Ghent, Belgium
关键词
polymer optical fiber; step-index fiber; biodegradable; bioresorbable; biomedical; polyester; optical polymers;
D O I
10.1117/12.2556161
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Biocompatible optical waveguides receive increasing attention owing to their application potential in the biomedical field. Our focus is on the fabrication and characterization of a new step-index biodegradable polymer optical fiber (bioPOF) using two commercial polyesters: poly(D,L-lactic-co-glycolic acid) (PDLGA) and poly(D,L-lactic acid) (PDLLA). Both polymers are regulated by US FDA, which allows projecting future clinical use of fibers made from these materials. We manufactured three preforms and we subsequently drew optical fibers with a standard heat-draw tower. We describe the chemical properties of the materials throughout the whole production chain from polymer granulates to preforms and then to optical fibers. We look into to the influence of the processing on the molecular weight and thermal characteristics of the polymers. Our step-index bioPOF with an outer diameter of 1000 +/- 50 mu m and a core of around 570 +/- 30 mu m features record low attenuation of 0.26 dB/cm at 950 nm for step index bioPOF, and a numerical aperture of 0.163 Immersion in phosphate-buffered saline (PBS) leads to hydrolytic degradation of the bioPOFs over a period of 3 months, accompanied with a 91% molecular weight loss. From the degradation study results, we anticipate that our bioPOFs can be used for biophotonic applications requiring deep tissue light delivery, such as photodynamic therapy.
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页数:10
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