Cord blood, a rich source of hematopoietic stem and progenitor cells, has been used for transplantation in both a sibling and an unrelated setting. More than 100 transplants have been done for a variety of nonmalignant diseases, including genetic immunodeficiencies and malignant disorders. The clinical results are encouraging and have demonstrated engraftment and low levels of graft-versus-host disease. Cord blood transplantation has been helped by the establishment of cord blood banks. Although there is much still to be learned regarding the biology, immunology, and transplantation of cord blood, the future of this form of transplantation is extremely promising.
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St Louis Univ, Ctr Hlth Sci, Cardinal Glennon Childrens Hosp, St Louis, MO 63103 USASt Louis Univ, Ctr Hlth Sci, Cardinal Glennon Childrens Hosp, St Louis, MO 63103 USA
Knutsen, AP
Wall, DA
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St Louis Univ, Ctr Hlth Sci, Cardinal Glennon Childrens Hosp, St Louis, MO 63103 USASt Louis Univ, Ctr Hlth Sci, Cardinal Glennon Childrens Hosp, St Louis, MO 63103 USA
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul 135710, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul 135710, South Korea
Lee, Myoung Woo
Jang, In Keun
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul 135710, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul 135710, South Korea
Jang, In Keun
Yoo, Keon Hee
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul 135710, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul 135710, South Korea
Yoo, Keon Hee
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Sung, Ki Woong
Koo, Hong Hoe
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul 135710, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul 135710, South Korea