Fabrication of PLGA/ (HA/CS) n/CD34 Bioactive Multiplayer Film on Stainless Steel Stent

被引：0

作者：

Li, Ying ^{[1
]}

Zhao, Hong ^{[2
]}

Zhang, Shixuan ^{[2
]}

机构：

[1] Vocat COll, Liaoning Geol Engn, Liaoning, Peoples R China

[2] Dalian Univ Technol, Dalian, Peoples R China

来源：

PROCEEDINGS OF THE 2015 INTERNATIONAL CONFERENCE ON SOCIAL SCIENCE AND TECHNOLOGY EDUCATION (ICSSTE 2015) | 2015年 / 18卷

关键词：

Electrostatic self-assembly; multilayer films; CD34; antibody; Polylactide-co-glycolide (PLGA); INTERVENTION;

D O I：

暂无

中图分类号：

G40 [教育学];

学科分类号：

040101 ; 120403 ;

摘要：

At present PLGA is widely used in clinical as a drug carrier in drug-eluting stent coating. But due to the existence of poor biological activity and easily cased thrombosis of PLGA, it is serious to increase the biological activity and hemocompatibility of drug-eluting stent. In this research, the paper try to fabricate PLGA/(HA/CS) n/CD34 bioactive multilayer films on biomedical 316L stainless steel (316LSS) surface via electrostatic self-assembly. Using fluorescent dyes to make the characterization of the films. It is considered the effect of corrosion resistance in blood about solution concentration and layers of multilayer films through blood washed simulation experiments. The research makes platelet adhesion experiment on multilayer films in different solution concentration and layers in order to optimize process parameters.

引用

页码：866 / 869

页数：4