Iron(III) acetylacetonate catalyzed tandem oxidative addition/cyclization of simple amides with alkenes: a convenient process to synthesize 3-amido oxindoles

被引:8
|
作者
Wang, Ruihong [1 ]
Bao, Weiliang [1 ]
机构
[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Zhejiang, Peoples R China
关键词
Amides; Iron catalysis; Oxindoles; Tendem CDC reaction; SP(3) C-H; DEHYDROGENATIVE COUPLING REACTIONS; BOND ADJACENT; NITROGEN-ATOM; TERMINAL ALKYNES; TERTIARY-AMINES; METAL; ALKYLATION; FUNCTIONALIZATION; ACTIVATION;
D O I
10.1016/j.tet.2015.07.005
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An iron catalyzed tandem oxidative addition/cyclization of amides with activated alkenes under mild conditions has been developed. The reaction provided a new amides derivation procedure and a synthetic methodology for 3-amido oxindoles. (C) 2015 Published by Elsevier Ltd.
引用
收藏
页码:6997 / 7002
页数:6
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