Sonochemical synthesis of novel pyrano[3,4-e][1,3]oxazines: A green protocol

被引：15
|
作者：
Saleh, Tamer S. [1 ,2 ]
Al-Bogami, Abdullah S. [1 ]
Mekky, Ahmed E. M. [1 ,3 ]
Alkhathlan, Hamad Z. [4 ]
机构：
[1] King Abdulaziz Univ, Fac Sci, Dept Chem, POB 80203, Jeddah 21589, Saudi Arabia
[2] Natl Res Ctr, Green Chem Dept, Cairo 12622, Egypt
[3] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt
[4] King Saud Univ, Coll Sci, Dept Chem, POB 2455, Riyadh 11451, Saudi Arabia
来源：
ULTRASONICS SONOCHEMISTRY | 2017年 / 36卷
关键词：
Ultrasound irradiation; KF/basic alumina; Pyrano[3,4-e][1,3]oxazine derivatives; Dimethyl carbonate(DMC); Atom economy; ULTRASOUND PROMOTED SYNTHESIS; ANTITUBERCULAR ACTIVITY; ANTIMICROBIAL ACTIVITY; ATOM ECONOMY; ONE-POT; REDUCTION; CHEMISTRY; CATALYSIS; PYRAZOLES; ANALOGS;
D O I：
10.1016/j.ultsonch.2016.12.015
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
The atom-efficient and green protocol for formation of pyrano[3,4-e][1,3]oxazines utilizing dimethyl carbonate under ultrasound irradiation in a presence of KF/basic alumina was reported. We provide a novel series of pyrano[3,4-e][1,3]oxazine derivatives interesting for biological screening tests. In general, it was found that ultrasound irradiations enable the reactions to occur which could not be carried out under silent conditions. These remarkable effects appeared in sonicated reactions can be reasonably interpreted in terms of acoustic cavitation phenomenon. Structures of the products were established on analytical and spectral data. This protocol offers several advantages attain many principles of green chemistry including, save energy, atom economy, clean reactions, inexpensive green reagent and use catalysts rather than stoichiometric reagents. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：474 / 480
页数：7
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