Total syntheses of squamocin A and squamocin D

被引：22
|
作者：
Emde, U [1 ]
Koert, U [1 ]
机构：
[1] Humboldt Univ, Inst Chem, D-10115 Berlin, Germany
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 33期
关键词：
D O I：
10.1016/S0040-4039(99)01225-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The total syntheses of two acetogenins, squamocin A and squamocin D, have been achieved. The adjacent bis-THF subunit was constructed by a multiple Williamson reaction. The left and the right side chain were added by addition of organomagnesium compounds to aldehyde functions. The conversion of a carboxylic acid into the butenolide moiety concluded both syntheses. (C) 1999 Elsevier Science Ltd. All rights reserved.
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页码：5979 / 5982
页数：4
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