PARKINSON'S DISEASE Disorder in the court

被引:10
|
作者
Alderson, T. Reid [1 ,2 ]
Bax, Ad [1 ]
机构
[1] NIDDK, Chem Phys Lab, NIH, Bethesda, MD 20892 USA
[2] Univ Oxford, Dept Chem, Oxford OX1 3TA, England
关键词
ALPHA-SYNUCLEIN; CELL NMR; MULTIMERS;
D O I
10.1038/nature16871
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The native structure of the protein α-synuclein, which is implicated in Parkinson's disease, is controversial. In-cell nuclear magnetic resonance now shows that it remains disordered when loaded into living cells. See Article p.45
引用
收藏
页码:38 / 39
页数:2
相关论文
共 50 条
  • [1] Is Parkinson's disease a prion disorder?
    Olanow, C. Warren
    Prusiner, Stanley B.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (31) : 12571 - 12572
  • [2] Parkinson's disease is a neuropsychiatric disorder
    Agid, Y
    Arnulf, I
    Bejjani, P
    Bloch, F
    Bonnet, AM
    Damier, P
    Dubois, B
    François, C
    Houeto, JL
    Iacono, D
    Karachi, C
    Mesnage, V
    Messouak, O
    Vidailhet, M
    Welter, ML
    Yelnik, J
    PARKINSON'S DISEASE, 2003, 91 : 365 - 370
  • [3] Parkinson's Disease: A Multisystem Disorder
    Helena Nunes Costa
    Ana Raquel Esteves
    Nuno Empadinhas
    Sandra Morais Cardoso
    Neuroscience Bulletin, 2023, 39 : 113 - 124
  • [4] Parkinson's disease: A circuit disorder
    DeLong, MR
    Wichmann, T
    MOVEMENT DISORDERS, 2006, 21 : S44 - S44
  • [5] Is Parkinson's disease a lysosomal disorder?
    Klein, Andres D.
    Mazzulli, Joseph R.
    BRAIN, 2018, 141 : 2255 - 2262
  • [6] Parkinson’s disease as a multisystem disorder
    Lisa Klingelhoefer
    H. Reichmann
    Journal of Neural Transmission, 2017, 124 : 709 - 713
  • [7] Parkinson's disease is NOT a prion disorder
    Roth, Jan
    CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE, 2016, 79 (01) : 23 - 23
  • [8] Psychiatric disorder and Parkinson's disease
    Tazi, I.
    Manoudi, F.
    Asri, F.
    EUROPEAN PSYCHIATRY, 2007, 22 : S246 - S247
  • [9] Parkinson's disease is an heterogeneous disorder
    Vidailhet, M
    BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 2003, 187 (02): : 259 - 275
  • [10] Cognitive disorder in Parkinson's disease
    Calabrese, P
    Skodda, S
    SCHWEIZERISCHE RUNDSCHAU FUR MEDIZIN PRAXIS, 2005, 94 (42): : 1647 - 1653