Anti-Breast Cancer Activity of a Novel Strategy of Targeting Autophagy Induced by Pan-HDAC Inhibitor and Acetylated Hsp70

被引：0
|
作者：
Rao, R. [1 ]
Nalluri, S. [1 ]
Bhalla, K. N. [1 ]
机构：
[1] Med Coll Georgia, Augusta, GA 30912 USA
来源：
CANCER RESEARCH | 2009年 / 69卷 / 24期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：687S / 687S
页数：1
相关论文
共 24 条
  • [1] Targeting autophagy induced by pan-HDAC inhibitor panobinostat and promoted by acetylated hsp70: A novel therapy for breast cancer
    Rao, Rekha
    Fiskus, Warren C.
    Yang, Yonghua
    Mudunuru, Uma
    Wang, Yongchao
    Atadja, Peter
    Bhalla, Kapil N.
    MOLECULAR CANCER THERAPEUTICS, 2009, 8 (12)
  • [2] Pan-HDAC inhibitor treatment sensitizes breast cancer cells to autophagy inhibitor 2-phenylethynesulfonamide: Molecular mechanism
    Rao, Rekha
    Nalluri, Srilatha
    Fiskus, Warren
    Mudunuru, Uma
    Bhalla, Kapil N.
    CANCER RESEARCH, 2010, 70
  • [3] Development of a novel pharmacological Hsp70 inhibitor with anti-myeloma activity
    Chatterjee, M.
    Sotriffer, C. A.
    Mueller, E.
    Peinz, U.
    Zilian, D.
    Hartung, A.
    Holzgrabe, U.
    Einsele, H.
    Bargou, R. C.
    ONKOLOGIE, 2012, 35 : 159 - 159
  • [4] A novel HSP70 inhibitor demonstrates potent anti-myeloma activity
    Bailey, Charvann K.
    Budina, Anna
    Murphy, Maureen
    Nefedova, Yulia
    CANCER RESEARCH, 2015, 75
  • [5] Artesunate, as a HSP70 ATPase activity inhibitor, induces apoptosis in breast cancer cells
    Pirali, Masoud
    Taheri, Maryam
    Zarei, Sevda
    Majidi, Mashad
    Ghafouri, Hossein
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 164 : 3369 - 3375
  • [6] A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction
    Wang, Ziqian
    Song, Ting
    Guo, Zongwei
    Uwituze, Laura B.
    Guo, Yafei
    Zhang, Hong
    Wang, Hang
    Zhang, Xiaodong
    Pan, Hao
    Ji, Tong
    Yin, Fangkui
    Zhou, Sheng
    Dai, Jian
    Zhang, Zhichao
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 220
  • [7] Study of novel ginsenoside metabolites targeting HSP70 as anti-prostate cancer drugs
    Xu, Lei
    Xiao, Shengnan
    Chai, Zhi
    Li, Tao
    Lee, Jung Joon
    Su, Guangyue
    Zhao, Yuqing
    BIOORGANIC CHEMISTRY, 2024, 144
  • [8] Targeting the HSP40/HSP70 chaperone axis as a novel strategy to treat castration-resistant prostate cancer
    Moses, Michael A.
    Kim, Yeong Sang
    Rivera-Marquez, Genesis
    Watson, Matthew J.
    Lee, Sunmin
    Kravats, Andrea
    Wickner, Sue
    Gestwicki, Jason
    Trepel, Jane
    Neckers, Len
    CANCER RESEARCH, 2017, 77
  • [9] Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer
    Moses, Michael A.
    Kim, Yeong Sang
    Rivera-Marquez, Genesis M.
    Oshima, Nobu
    Watson, Matthew J.
    Beebe, Kristin E.
    Wells, Catherine
    Lee, Sunmin
    Zuehlke, Abbey D.
    Shao, Hao
    Bingman, William E., III
    Kumar, Vineet
    Malhotra, Sanjay V.
    Weigel, Nancy L.
    Gestwicki, Jason E.
    Trepel, Jane B.
    Neckers, Leonard M.
    CANCER RESEARCH, 2018, 78 (14) : 4022 - 4035
  • [10] YK5 is a novel dual Hsc/Hsp70 inhibitor that is selective for tumor Hsp70 and is a valuable lead for the development of molecules with therapeutic potential in breast cancer
    Taldone, Tony
    Kang, Yanlong
    Rodina, Anna
    Maharaj, Ronnie
    Gozman, Alexander
    Cerchietti, Leandro
    Wong, Michael J. H.
    Baaklini, Imad
    Caldas-Lopes, Eloisi
    Patel, Hardik J.
    Clement, Cristina C.
    Brodsky, Jeffrey
    Melnick, Ari
    Young, Jason C.
    Chiosis, Gabriela
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 241
123