A MULTIPLE IMPUTATION PROCEDURE FOR RECORD LINKAGE AND CAUSAL INFERENCE TO ESTIMATE THE EFFECTS OF HOME-DELIVERED MEALS

被引:0
|
作者
Shan, Mingyang [1 ]
Thomas, Kali S. [2 ]
Gutman, Roee [1 ]
机构
[1] Brown Univ, Dept Biostat, Sch Publ Hlth, Providence, RI 02912 USA
[2] Brown Univ, Dept Hlth Serv Policy & Practice, Sch Publ Hlth, Providence, RI 02912 USA
来源
ANNALS OF APPLIED STATISTICS | 2021年 / 15卷 / 01期
关键词
Record linkage; missing data; causal inference; multiple imputation; Bayesian data analysis; PRINCIPAL STRATIFICATION; OLDER-ADULTS; STATISTICAL-INFERENCE; REGRESSION ADJUSTMENT; BINARY TREATMENTS; REMOVE BIAS; PROGRAMS; OUTCOMES;
D O I
10.1214/20-AOAS1397
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Causal analysis of observational studies requires data that comprise a set of covariates, a treatment assignment indicator and the observed outcomes. However, data confidentiality restrictions or the nature of data collection may distribute these variables across two or more datasets. In the absence of unique identifiers to link records across files, probabilistic record linkage algorithms can be leveraged to merge the datasets. Current applications of record linkage are concerned with estimation of associations between variables that are exclusive to one file and not causal relationships. We propose a Bayesian framework for record linkage and causal inference where one file comprises all the covariate and observed outcome information, and the second file consists of a list of all individuals who receive the active treatment. Under certain ignorability assumptions, the procedure properly propagates the error in the record linkage process, resulting in valid statistical inferences. To estimate the causal effects, we devise a two-stage procedure. The first stage of the procedure performs Bayesian record linkage to multiply-impute the treatment assignment for all individuals in the first file, while adjustments for covariates' imbalance and imputation of missing potential outcomes are performed in the second stage. This procedure is used to evaluate the effect of Meals on Wheels services on mortality and healthcare utilization among homebound older adults in Rhode Island. In addition, an interpretable sensitivity analysis is developed to assess potential violations of the ignorability assumptions.
引用
收藏
页码:412 / 436
页数:25
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