Hyaline-vascular type Castleman's disease involving both orbits

Purpose: To describe a patient with hyaline-vascular type Castleman's disease (CD) whose initial examination revealed only upper eyelid mass. Further, to review all aspects of CD. Methods: Case report. An 18-year-old woman initially presented with swelling of both upper eyelids. She underwent an anterior orbitotomy with surgical excision followed by close observation. Results: Histopathological examination of the upper eyelid mass confirmed the presence of hyaline-vascular type CD. One year after surgical treatment, the patient is still asymptomatic, with no pathologic clinical or laboratory findings. Conclusions: Castleman's disease is a rare but valid clinical entity. It should be considered in the differential diagnosis of asymptomatic orbital mass. Our understanding of CD has advanced recently. The treatment modalities for CD (e.g. surgical excision, radiation therapy and combination chemotherapy) are usually curative and optimizing. Castleman's disease involving the orbital area is now attracting ophthalmological interest.