Update on Albumin Therapy in Critical Illness

被引：31
|
作者：
Mazzaferro, Elisa M. [1 ,2 ]
Edwards, Thomas [3 ]
机构：
[1] Cornell Univ Vet Specialists, 880 Canal St, Stamford, CT 06902 USA
[2] Cornell Univ Hosp Anim, Emergency & Crit Care, Ithaca, NY 14853 USA
[3] US Army Inst Surg Res, Res Support Div, 3698 Chambers Pass, San Antonio, TX 78234 USA
来源：
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE | 2020年 / 50卷 / 06期
关键词：
Albumin; Colloid osmotic pressure; Endothelial glycocalyx; Type III hypersensitivity reaction; Transfusion; HUMAN SERUM-ALBUMIN; ACUTE KIDNEY INJURY; ILL DOGS; CRYOPOOR PLASMA; III HYPERSENSITIVITY; HEALTHY DOGS; PRESSURE; DISEASE; SEPSIS; SUPPLEMENTATION;
D O I：
10.1016/j.cvsm.2020.07.005
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Albumin is among the most important proteins and plays a significant role in maintenance of colloid osmotic pressure, wound healing, decreasing oxidative damage, carrying drugs and endogenous substances, and coagulation. Hypoalbuminemia is common in acute and chronic illnesses. Replenishment of albumin can be in the form of fresh frozen, frozen or cryopoor plasma, or in the form of human or canine albumin concentrates. Infusion of human albumin concentrate to healthy and critically ill dogs can induce acute and delayed hypersensitivity reactions. Death has been reported. Therefore, allogenic transfusion in the form of plasma products or canine albumin concentrate is recommended. © 2020 Elsevier Inc.
引用
收藏
页码：1289 / 1305
页数：17
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