The functional role of molecular clustering in the center of the immunological synapse is controversial. In this issue of Immunity, Oemerski et al. (2008) report that the synapse center can serve as a major site of sustained signal transduction.
机构:
NYU, Sch Med, Skirball Inst Biomol Med, Dept Pathol, 540 1st Ave, New York, NY 10016 USANYU, Sch Med, Skirball Inst Biomol Med, Dept Pathol, 540 1st Ave, New York, NY 10016 USA